Press Releases

Leonard Osser, CEO

Milestone Scientific Inc. Regains Compliance with American Stock Exchange Continued Listing Standards

August 23, 2005

Livingston, New Jersey. – August 23, 2005 – Milestone Scientific Inc. (AMEX: MS) today announced that it has received notice from the American Stock Exchange that it has regained compliance with all continued listing requirements. Milestone had been notified by the AMEX on January 4, 2005 that it was below the continued listing standard requiring stockholder equity of $6 million.

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About Milestone Scientific Inc.

Milestone Scientific is the developer, manufacturer and marketer of CompuMed® and CompuDent® computer controlled local anesthetic delivery systems. These systems comprise a microprocessor controlled drive unit as well as The Wand® handpiece, a single patient use product that is held in a pen-like manner for injections. The Company also sells the SafetyWand®, which incorporates engineered sharps injury protection features to aid in the prevention of accidental needlesticks. Milestone has also developed proprietary consumer (Ionic White) and professional (Cool Blue) teeth whitening systems that were introduced to the market in early 2005.

In 2001, Milestone Scientific received broad United States patent protection on an enabling technology for computer controlled, pressure sensitive infusion, perfusion, suffusion and aspiration, which provides real time displays of pressures, fluid densities and flow rates, that advances the delivery and removal of a wide array of fluids. Development of this CompuFlo technology is currently underway.

The Company is headquartered in Livingston, New Jersey, and its common stock trades on the American Stock Exchange under the symbol “MS”.